GRANULAR CELL TUMOR (GCT)Perspektif Klinis, Histopatologis, dan Onkologi Molekuler Kontemporer
Keywords:
kedokteran, kesehatanSynopsis
Buku ini disusun di tengah pesatnya perkembangan ilmu kedokteran, khususnya dalam ranah onkologi dan patologi anatomi. Granular Cell Tumor (GCT) atau yang secara historis dikenal sebagai Abrikossoff Tumor, merupakan salah satu entitas neoplasma klonal jaringan lunak yang relatif langka namun menyimpan kompleksitas diagnostik yang sangat tinggi. Karakteristik sitologisnya yang unik sering kali bertindak sebagai peniru ulung (the great mimicker) bagi keganasan lain, sehingga menuntut pemahaman yang komprehensif, tidak hanya dari manifestasi klinis luarnya, melainkan hingga ke tingkat biologi molekuler dan genetika seluler.
Kehadiran buku ini diharapkan dapat mengisi ruang literatur medis berbahasa Indonesia yang secara khusus membedah GCT dari hulu ke hilir. Di dalamnya, penulis berupaya merajut paradigma patologi klasik dengan temuan-temuan onkologi presisi paling mutakhir, termasuk pergeseran teori histogenesis menuju silsilah neurogenik sel Schwann, disfungsi kompleks pompa proton v-ATPase lisosom, hingga hiperaktivasi jalur pensinyalan kontemporer mTORC1. Lebih dari sekadar teori abstrak, buku ini juga diperkaya dengan data epidemiologi, visualisasi skema, matriks risiko, komplikasi, hingga studi kasus riil guna memberikan panduan taktis bagi para klinisi, residen, mahasiswa kedokteran, dan praktisi laboratorium patologi.
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Published
June 27, 2026
Copyright (c) 2026 Lalu Fauzan Adi Yuliansyah, Hidmi Gramatolina Ramdhayani (Author)
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Adi Yuliansyah, L. F., & Gramatolina Ramdhayani, H. (2026). GRANULAR CELL TUMOR (GCT)Perspektif Klinis, Histopatologis, dan Onkologi Molekuler Kontemporer. Widina Media Utama. https://doi.org/10.59818/1jx70d76
